Should novel agents be used prior to transplant in MDS-EB1/2?

During the 6th International Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM 2021), the MDS Hub was...

How can we predict drug resistance in high-risk MDS?

During the 16th International Congress on Myelodysplastic Syndromes (MDS 2021), the MDS hub was pleased to speak to Mikkael Sekeres, Sylvester...

Post-transplant maintenance therapy: low dose decitabine + venetoclax is safe and effective for high-risk AML and MDS

Both acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) are...

What treatment would you suggest for high risk MDS patients not fit for chemotherapy or HSCT?

During the Society of Hematologic Oncology (SOHO) 2021 Annual Meeting, the MDS Hub spoke with Andrew...

Double minute chromosomes associated with rare cytogenetic abnormalities and poor prognosis in MDS and AML

Double minute chromosomes (DM) are circular extrachromosomal DNA fragments, which can...

Prevalence and impact of PPM1D mutations in patients with MDS and del(5q)

Mutations in the PPM1D gene drive clonal hematopoiesis and occur in various malignancies.

How should molecular profiling be used to guide MDS therapy?

During the Acute Leukemia Forum (ALF) 2021, the MDS Hub spoke to Rafael Bejar, UC San Diego, San Diego, US. We asked, How should molecular...

Germline mutations in patients with hematologic malignancies

Germline mutations in patients with neoplasms are more common than expected and have been found not only in children but also adults with...

Prevalence and impact of PPM1D mutations in patients with MDS and del(5q)

Mutations in the PPM1D gene drive clonal hematopoiesis and occur in various malignancies.

Editorial theme | Immune dysregulation and genetic mutations associated with MDS pathogenesis

The pathogenesis of myelodysplastic syndromes (MDS) is heterogeneous, involving inflammation, cytokines,...

What is new for MDS with del(5q)?

During the7th European School of Haematology (ESH) Translational Research Conference on Myelodysplastic Syndromes, the MDS Hub spoke to María Díez Campelo,...

Updated ESMO clinical practice guidelines for diagnosis, treatment, and follow-up of MDS

The European Society for Medical Oncology (ESMO) Guidelines Committee issued an update of their Clinical...