What treatment would you suggest for high risk MDS patients not fit for chemotherapy or HSCT?

During the Society of Hematologic Oncology (SOHO) 2021 Annual Meeting, the MDS Hub spoke with Andrew...

Personalized prediction model for risk stratification in patients with MDS

Patients with myelodysplastic syndromes (MDS) present with heterogenous clinical outcomes, with some patients living longer...

Safety and effectiveness of DEC plus VEN as a maintenance therapy in patients with high-risk AML and MDS

Acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) are typically associated with...

EPICOVIDEHA registry: Epidemiology and outcomes in patients with hematologic malignancies infected with COVID-19

Patients with hematologic malignancies (HMs) may have intensified immune dysregulation...

Double minute chromosomes associated with rare cytogenetic abnormalities and poor prognosis in MDS and AML

Double minute chromosomes (DM) are circular extrachromosomal DNA fragments, which can...

Prevalence and impact of PPM1D mutations in patients with MDS and del(5q)

Mutations in the PPM1D gene drive clonal hematopoiesis and occur in various malignancies.

How should molecular profiling be used to guide MDS therapy?

During the Acute Leukemia Forum (ALF) 2021, the MDS Hub spoke to Rafael Bejar, UC San Diego, San Diego, US. We asked, How should molecular...

Germline mutations in patients with hematologic malignancies

Germline mutations in patients with neoplasms are more common than expected and have been found not only in children but also adults with...

Prevalence and impact of PPM1D mutations in patients with MDS and del(5q)

Mutations in the PPM1D gene drive clonal hematopoiesis and occur in various malignancies.

Editorial theme | Immune dysregulation and genetic mutations associated with MDS pathogenesis

The pathogenesis of myelodysplastic syndromes (MDS) is heterogeneous, involving inflammation, cytokines,...

What is new for MDS with del(5q)?

During the7th European School of Haematology (ESH) Translational Research Conference on Myelodysplastic Syndromes, the MDS Hub spoke to María Díez Campelo,...

Updated ESMO clinical practice guidelines for diagnosis, treatment, and follow-up of MDS

The European Society for Medical Oncology (ESMO) Guidelines Committee issued an update of their Clinical...