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Myelodysplastic syndromes
Myelodysplastic syndromes
Myelodysplastic syndromes (MDS) comprise several hematopoietic disorders characterized by morphological changes in bone marrow cells, peripheral cytopenia, and overall bone marrow failure. According to the 2016 World Health Organization (WHO) criteria, MDS can be classified as single or multilineage dysplasia, with ring sideroblasts, excess blasts, or with del(5q) cytogenetic abnormality. MDS may progress to acute myeloid leukemia (AML).