All content on this site is intended for healthcare professionals only. By acknowledging this message and accessing the information on this website you are confirming that you are a Healthcare Professional. If you are a patient or carer, please visit the MDS Alliance.
Now you can personalise
your MDS Hub experience!
Bookmark content to read later
Select your specific areas of interest
View content recommended for youFind out more
The accumulation of mutations drives disease evolution from asymptomatic clonal hematopoiesis to MDS. The study and identification of MDS-related mutations can be crucial for diagnosis, risk stratification, and, ultimately, therapy decision. Most MDS cases are caused by somatic mutations in DNMT3A, TET2, SF3B1, and TP53, but they can also be caused by inherited mutations in genes like DKC1, TERC, RUNX1, ETV6, GATA2, or SBDS.
Save to your areas of interest