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What hematologic toxicities occur after venetoclax + azacitidine in MDS and how can they be managed?

Featured:

Vinod PullarkatVinod Pullarkat

Jun 25, 2021


During the EHA2021 Virtual Congress, the MDS Hub spoke with Vinod Pullarkat, City of Hope Comprehensive Cancer Center, Duarte, US. We asked, What hematologic toxicities occur after venetoclax + azacitidine in MDS and how can they be managed? 

What hematologic toxicities occur after venetoclax + azacitidine in MDS and how can they be managed?

Pullarkat discusses the hematoloigc toxicities associated with venetoclax and azacitidine, which are largely related to cytopenias. He explains that the key to managing these toxicities is close monitoring of patients and providing transfusion support as needed. Finally, he mentions that a high percentage of patients will require dose modifications.