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Should novel agents be used prior to transplant in MDS-EB1/2?

During the 6th International Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM 2021), the MDS Hub was pleased to speak to Uwe Platzbecker, University of Leipzig Medical Center, Leipzig, DE. We asked, Should novel agents be used prior to transplant in MDS-EB1/2?

Should novel agents be used prior to transplant in MDS-EB1/2?

In this video, Platzbecker discusses whether high-risk MDS patients with excess blasts should be treated with novel agents prior to allogenic stem cell transplantation. Platzbecker also discusses the use of combination therapy.