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Phase III Dacota trial: Will hydroxyurea remain SoC for advanced proliferative CMML?

By Paola Frisone

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Raphael ItzyksonRaphael Itzykson

Feb 5, 2021


During the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, the MDS Hub spoke to Raphael Itzykson, Université de Paris, Paris, FR, about the phase III Dacota trial. We asked, Will hydroxyurea remain standard of care for advanced proliferative chronic myelomonocytic leukemia (CMML)?

Phase III Dacota trial: Will hydroxyurea remain SoC for advanced proliferative CMML?

Itzykson discusses the results from the randomized phase III Dacota trial evaluating decitabine versus hydroxyurea in patients with advanced proliferative CMML.